Comprehensive Wrinkle Treatment
What are facial wrinkles, and why is”comprehensive treatment plan”?
Our physician’s Real Cases: Comprehensive Full-Face Wrinkle Treatment
The following before-and-after photos are authentic clinical records of real clients treated personally by our physician at Luowei Medical Aesthetics Clinic (Nanjing) for Facial Comprehensive Wrinkle Treatment. All clients have signed a written Media Release Form authorizing public use. All photos are unretouched clinical records. Individual results vary significantly based on muscle tone, skeletal support, skin collagen status, age, sun protection habits, and other factors.“Comprehensive Wrinkle Treatment” is not “treating wrinkles wherever they appear”, but rather A systematic plan addressing dynamic lines, static lines, and overall facial rejuvenation— This is a core area of expertise for our physician as a dual North America Trainer for both Botox® and Juvéderm® under Allergan.
Case 1 · Comprehensive Wrinkle Treatment — Authentic Record
- Client profile
- Asian Female · Fitzpatrick IV
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- PicoSure® + PicoSure Pro® + PicoWay® + Ultherapy® and 17 additional modalities (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- 9-12 months later, filler touch-up
Case 01: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick IV · Multimodal Combination Protocol led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 3 · Comprehensive Wrinkle Treatment — Real Results
- Client profile
- Asian Female · Fitzpatrick IV
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- Botox® + neurotoxin wrinkle treatments + Dysport® + Xeomin® and 7 related items (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- Botox 4 months of maintenance
Case 03: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick IV · Multimodal Combination Protocol Led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 3 · Comprehensive Wrinkle Treatment — Real Results
- Client profile
- Asian Female · Fitzpatrick IV
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- HArmonyCa™ hyaluronic acid collagen stimulator + collagen (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- regular sun protection + monthly at-home care + quarterly clinical assessments
Case 03: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick IV · Multimodal Combination Protocol Led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 4 · Comprehensive Wrinkle Treatment — Real Results
- Client profile
- Asian Male · Fitzpatrick IV
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- Thread double-eyelid procedure + Botox® + Dysport® + Xeomin® and 5 additional treatments (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- Botox 4 months of maintenance
Case 04: Comprehensive Wrinkle Treatment — Before & After · Asian Male · Fitzpatrick IV · Multimodal combination approach led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 4 · Comprehensive Wrinkle Treatment — Real Results
- Client profile
- Asian Female · Fitzpatrick I · Results maintained approximately 2–3 years
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- Hyaluronic acid dermal fillers + under-eye rejuvenation / tear-trough injections (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- 6–12 month follow-up · touch-up as needed + daily eye cream maintenance at home
Case 04: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick I · Results Maintained ~2–3 Years · Multimodal Combination Protocol Led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 4 · Comprehensive Wrinkle Treatment — Real Results
- Client profile
- Asian Female · Fitzpatrick IV
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- Dual picosecond combination therapy + PicoSure® skin brightening & rejuvenation + PicoSure Pro® and 8 additional treatments (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- regular sun protection + monthly at-home care + quarterly clinical assessments
Case 04: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick IV · Multimodal combination plan led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 5 · Comprehensive Wrinkle Treatment — Real Clinical Record
- Client profile
- Asian Female · Fitzpatrick IV
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- Dual picosecond combination therapy + skin brightening + PicoSure® + PicoSure Pro® and 9 additional treatments (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- regular sun protection + monthly at-home care + quarterly clinical assessments
Case 05: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick IV · Multimodal Combination Protocol led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 7 · Comprehensive Wrinkle Treatment — Authentic Record
- Client profile
- Asian Female · Fitzpatrick I · Results maintained approximately 2–3 years
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- Hyaluronic acid dermal fillers + under-eye rejuvenation / tear-trough injections (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- 6–12 month follow-up · touch-up as needed + daily eye cream maintenance at home
Case 07: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick I · Results maintained approximately 2–3 years · Multimodal combination plan led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 8 · Comprehensive Wrinkle Treatment — Real Results
- Client profile
- Asian Female · Fitzpatrick I · Results maintained approximately 2–3 years
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- Hyaluronic acid dermal fillers + under-eye rejuvenation / tear-trough injections (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- 6–12 month follow-up · touch-up as needed + daily eye cream maintenance at home
Case 08: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick I · Results maintained approximately 2–3 years · Multimodal combination approach led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 9 · Comprehensive Wrinkle Treatment — Real Results
- Client profile
- Asian Female · Fitzpatrick I · Results maintained approximately 2–3 years
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- Hyaluronic acid dermal fillers + under-eye rejuvenation / tear-trough injections (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- 6–12 month follow-up · touch-up as needed + daily eye cream maintenance at home
Case 09: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick I · Results Sustained ~2–3 Years · Multimodal Combination Protocol led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 10 · Comprehensive Wrinkle Treatment — Real Results
- Client profile
- Asian Female · Fitzpatrick I · Results maintained approximately 2–3 years
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- Hyaluronic acid dermal fillers + under-eye rejuvenation / tear-trough injections (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- 6–12 month follow-up · touch-up as needed + daily eye cream maintenance at home
Case 10: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick I · Results Maintained ~2–3 Years · Multimodal Combination Protocol Led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
Case 14 · Comprehensive Wrinkle Treatment — Real Clinical Record
- Client profile
- Asian Female · Fitzpatrick I · Results maintained approximately 2–3 years
- Areas of concern
- Comprehensive Wrinkle Treatment (multimodal combination approach for overall rejuvenation)
- Treatment plan
- Hyaluronic acid dermal fillers + under-eye rejuvenation / tear-trough injections (multiple sessions within 3 months)
- Treatment outcomes
- Significant improvement in overall wrinkles · natural-looking results
- post-inflammatory hyperpigmentation (PIH) risk
- No PIH
- maintain
- 6–12 month follow-up · touch-up as needed + daily eye cream maintenance at home
Case 14: Comprehensive Wrinkle Treatment — Before & After · Asian Female · Fitzpatrick I · Results maintained approximately 2–3 years · Multimodal combination plan led by our physician at Luowei Medical Aesthetics Clinic, Nanjing
What are facial wrinkles, and why is “comprehensive treatment plan”?
Facial wrinkles are classified by mechanism into Dynamic lines + static lines + volume-loss wrinkles + surface texture four major categories, which often coexist but each require A completely different treatment approach. This is why “treating wrinkles wherever they appear” is the wrong approach; the correct approach is Layered diagnosis + comprehensive treatment plan.
The 4 Major Types of Facial Wrinkles
Dynamic Wrinkles
Caused by repeated contraction of the mimetic muscles — crow’s feet when smiling, glabellar lines when frowning, and horizontal forehead lines when raising the brows.Not visible or only faint at rest, Most visible during facial expression. Botox® is the gold standard.
Static Wrinkles
Long-standing dynamic lines combined with collagen loss → lines remain visible even at rest.Botox A single treatment is no longer sufficient, requires combination filler and/or energy-based collagen regeneration.
Volume Loss Lines
Zygomatic fat loss → deepening nasolabial folds; tear trough volume deficit → prominent under-eye bags. For this type of wrinkle, “Root cause” is volume loss,Botox completely ineffective, Structural filler support is essential.
Surface Texture Wrinkles
Fine lines, enlarged pores, and rough texture caused by photoaging. Requires epidermal treatment: Laser resurfacing, chemical peels, HydraFacial®, and medical-grade skincare.
All four types frequently coexist — only a comprehensive approach is truly effective.
40+ The vast majority of our clients present with all four types of wrinkles simultaneously.Botox® only: Dynamic lines resolved, but static lines remain;Fillers only: Volume is restored, yet dynamic lines continue to deepen with expression;Laser only: Surface improvements achieved, but underlying aging left unaddressed.comprehensive treatment plan can true rejuvenation be achieved.
Facial Wrinkles by Location (7 Common Zones)
- Forehead lines (Frontalis) — dynamic lines, Botox® is the first-line treatment
- Glabellar lines (corrugator supercilii + depressor supercilii) — dynamic lines, often combined with static deep furrows
- Crow’s feet (orbicularis oculi) — dynamic lines; Baby Botox delivers the most natural result
- Bunny lines (Nasalis) — diagonal nasal lines when smiling, low-dose Botox®
- Nasolabial folds (nasolabial folds) — primarily driven by volume loss; filler is the primary treatment
- Marionette lines (Below the corners of the mouth) — volume loss combined with overactive DAO muscle; a comprehensive approach is indicated
- Horizontal neck lines (Tech Neck)— see the Turkey Neck page
3 common composite aging patterns
30+ Early-stage · Preventive
Primarily dynamic lines — low-dose preventive Botox® + foundational hydration + daily sun protection.“Prevention costs a fraction of correction”.
40+ Intermediate · Combination Type
Mixed dynamic and static lines + early volume loss. Botox® + filler + early-stage energy-based radiofrequency, “Liquid lift” concept.
50+ Comprehensive · multi-layer plan
All four layers of aging addressed. Multimodal combination therapy with phased execution — completed over 6–9 months, with an overall rejuvenating effect of 8–10 years.
6 step self-assessment
- When making facial expressions Forehead / glabellar area / periorbital area Are visible lines present?
- after the expression fades whether lines remain visible?
- Facial zygomatic / mid-face Is there noticeable volume loss?
- Nasolabial folds / marionette lines Has it deepened?
- Overall skin Is skin texture rough??
- Feel you look older than your peers Aged / tired / stern?
3 or more treatments “yes”, A comprehensive treatment plan evaluation is recommended. Accurate layered diagnosis requires an in-person consultation, dynamic video assessment, and physical examination.
The Causes of Facial Wrinkles (6 Key Mechanisms)
Without understanding the underlying mechanism, it is impossible to choose the right treatment. Similarly, “Nasolabial folds”, Younger patients typically present with muscle-driven concerns (addressed with Botox®), middle-aged patients with volume loss (addressed with Filler), and older patients with a combination of both (Filler + energy-based treatments) — each requiring a fundamentally different approach.
Repetitive contraction of mimetic muscles (the root cause of dynamic lines)
The mimetic muscles — including the frontalis, corrugator, and orbicularis oculi — contract millions of times over a lifetime. Each contraction folds the overlying skin, gradually creating creases in the dermis that begin as dynamic lines and eventually become static lines. The more expressive you are, the earlier these lines tend to appear.
Loss of collagen and elastin (the foundation of static lines)
25 After a certain age, dermal collagen decreases by approximately 1% per year. Collagen provides both elasticity and structural support. Once lost, the skin can no longer spring back — and dynamic crease lines “preserve” Transition to static lines.
Bone and fat pad loss (volumetric lines)
40+ Cheekbone resorption + descent of the malar fat pad → mid-face “Volume collapse” → Nasolabial folds “pulled deeper”. This is structural concerns, is not “Skin concerns”.
Ligament laxity (sagging)
Facial retaining ligaments (zygomatic ligaments, masseteric cutaneous ligaments, etc.) gradually loosen with age → mid and lower face descent → deepening marionette lines + jowling + loss of jawline definition.
Photoaging (UV + epidermal damage)
UV directly degrades collagen and elastin, causes pigmentation, and roughens skin texture.Accounts for over 80% of facial aging! This is “Biological age vs. perceived age” the primary driver of this difference.
Lifestyle factors (smoking, sleep, stress, glycation)
Smoking: one of the strongest independent contributors to deep perioral lines. Poor sleep: impaired skin repair. Chronic stress: elevated cortisol → accelerated collagen breakdown. High-sugar diet: glycation damages collagen.
True dynamic lines vs. static lines vs. volume-related wrinkles vs. surface texture lines
Different types of wrinkles require different treatments — misdiagnosis means spending money without getting the results you want. The table below helps you understand the key differences in how each of the four major wrinkle categories is approached.
Pure dynamic lines
| Identify | Not visible at rest |
| Age | typically ages 25–40 |
| Plan | Botox Effective on its own |
| mistake | Using filler to treat dynamic lines |
| maintain | 3–4 month |
Mixed dynamic and static lines
| Identify | Visible even at rest |
| Age | Typically ages 35–55 |
| Plan | Botox + Superficial filler / energy-based treatment |
| mistake | Botox® alone (static lines remain unchanged) |
| maintain | Botox 4 months + filler at 12 months |
Volume loss lines
| Identify | deep static furrows · present regardless of expression |
| Typical | Nasolabial folds / cheek hollowing / tear troughs |
| Plan | Structural filler (Juvéderm® Voluma) |
| mistake | treating nasolabial folds with Botox |
| maintain | 12–24 month |
Epidermal texture
| Identify | Fine lines + enlarged pores + pigmentation |
| Typical | photoaging / acne marks |
| Plan | Laser + resurfacing + skincare |
| mistake | treating texture concerns with injectables |
| maintain | Regular surface-level skincare |
The Distinct Pattern of Asian Facial Aging
The aging trajectory of Asian faces differs fundamentally from that of Western faces — applying Western protocols directly is the root cause of poor outcomes.
1. Skeletal differences — more prominent cheekbones and jaw angles
Skeletal characteristics of East Asian patients:Wider cheekbones, more prominent jaw angles, and a relatively shorter mid-face. This means:
- the impact of volume loss on the face “hollow appearance” Relatively minimal impact
- sagging has a proportionally greater impact on the jawline
- Treatment priorities differ from those used for Western patients
2. aging pattern — “Sagging > Hollowing”
Western facial aging is primarily characterized by “hollowness” Predominantly driven by loss of malar fat and mid-face volume collapse; Asian facial aging is characterized by “Predominantly sagging / ptosis”(retaining ligament laxity + descent of the buccal fat pad). This is why treatment plans for Asian patients often:
- Energy-based radiofrequency (Sofwave™) takes priority
- More conservative filler dosing
- Avoid over-volumizing, which can result in “round and full”
3. Skin characteristics — oilier, thicker, and more prone to pigmentation
Asian skin tends to be oilier, with a thicker dermis, yet is more prone to post-inflammatory hyperpigmentation (PIH).
Age × combination approach (Asian female)
| Age | Primary concerns | Recommended plan |
|---|---|---|
| 25–30 | preventive | SPF + Medical-grade skincare + early-stage Baby Botox® |
| 30–35 | Early-stage dynamic lines | Botox + Skinvive + SPF |
| 35–45 | dynamic + static lines + early volume loss | Botox + mid-face filler + Sofwave™ |
| 45–55 | Generalized facial sagging | Multimodal + phased approach |
| 55+ | in-depth comprehensive | “Liquid Facelift” + Consider surgical options |
Comprehensive Wrinkle Treatment Plan (dynamic + static + volume + surface)
“comprehensive treatment plan” The core principle is: address each of the four wrinkle types with the right tools, executed in phases over 3–6 months, for harmonious full-face rejuvenation. Energy-based options fall into two families that are not interchangeable: radiofrequency skin tightening and ultrasound lifting. Which family fits depends on the tissue layer involved, not on which device is best known.
Botox® full upper-face protocol First-choice for dynamic lines
A comprehensive protocol addressing the frontalis, corrugator supercilii, depressor supercilii, and orbicularis oculi — standard range 20–60 units. Our physician approaches this with “Precise dosing + natural expression” as the guiding principle — ensuring clients never experience “Stiffness / frozen sensation”.
- 2 full effect at 2 weeks · duration 3.5–4 months
- Prevention + treatment of dynamic lines
- Without compromising natural expression
- 30+ most effective for prevention starting
Juvederm Voluma XC Mid-face support First-line treatment for volume-loss lines
Allergan Highest-support dermal filler, injected deeply to rebuild cheekbone structural support → Mid-face “Lifting”→ Nasolabial folds visibly soften and the overall appearance looks 5–8 years younger. Results last 18–24 months.
Volift / Volbella Superficial fine-line filler Static wrinkles
Different formulations target different areas: Volift for moderate nasolabial folds and marionette lines; Volbella for superficial fine lines under the eyes, around the lips, and on the lips.ultra-precise micro-amounts, Avoid “an unnatural look”.
Sofwave® Full-face tightening First-line for ligament laxity
NMPA-registered Synchronized UltraSound Energy for Body (SUPERB) technology that stimulates deep dermal collagen regeneration, lifts the mid and lower face, and refines the jawline. A single treatment with visible results from 3 months, lasting 18–24 months.
PicoSure Pro® 755nm Skin resurfacing + rejuvenation Epidermal texture
FOCUS The Focus Lens Array stimulates collagen regeneration while improving pore appearance, pigmentation, and fine lines. Recommended as a course of 3–4 sessions.
Skinvive Full-face microdroplet injection First-choice for hydration
Allergan Skinvive The micro-droplet injection technique improves overall skin hydration, fine lines, and luminosity. Commonly included in combination plans for clients 35+, with results lasting approximately 6 months.
Medical-grade skincare + SPF 50+ Foundation
In-clinic treatments account for 30%; daily skincare accounts for 70%. Core protocol:
- morning: Vitamin C antioxidant serum + SPF 50+ mineral sunscreen
- Evening: Retinol (gradually introduced) + ceramide barrier repair
- Weekly: Gentle acid treatment 1–2 sessions
- overall: Adequate hydration + quality sleep + reduced sugar intake + smoking cessation
Comprehensive plan template (by age group)
| Age | comprehensive treatment plan | timeline |
|---|---|---|
| 25–30 Prevention | Baby Botox Full upper face + Juvéderm® Skinvive full face | Botox® every 4 months + Skinvive every 6 months |
| 30–40 Early stage | Botox + Low-volume mid-face filler + PicoSure® × 3 sessions | Executed over 3 months |
| 40–50 Mid-stage | Botox + Voluma + Sofwave + Skinvive | Delivered over 4 months |
| 50–60 Comprehensive | Multimodal combination (full plan) + possible DAO muscle treatment | Executed over 6 months |
| 60+ Depth | multimodal approach + surgical consultation recommended | over 6–9 months |
Our physician’s 6-Step Full-Face Comprehensive Wrinkle Treatment Protocol
The essence of a comprehensive plan is not “Using many products”, but rather “Precise diagnosis + prioritization + staged execution”.
Full-face layered assessment
- Static frontal + 45° + 90° views Photography
- Dynamic video: smiling, frowning, raising the brows, pursing the lips, laughing
- Palpation: Volume, bone structure, retaining ligaments, and skin laxity
- Assess skin surface: pigmentation, pores, and texture
- lifestyle questionnaire: sun protection, sleep, stress management, and nutrition
Four-layer classification diagnosis
Identify which category each zone belongs to:
- Dynamic lines → Botox
- Superficial static lines → superficial filler / energy-based treatment
- Volume-loss lines → structural fillers
- Epidermal texture → laser / resurfacing
- Primarily sagging → Sofwave™ + fillers
Establishing treatment priorities
is not “doing everything in one session”, yes“which treatments come first, which follow, and why”:
- Structural concerns are addressed first (volume + retaining ligaments)
- Dynamic concerns can be addressed at any time (Botox®)
- Surface-level concerns are addressed last (to avoid interfering with other treatments)
- Prioritize the areas of greatest concern to the client
Design a phased 3–6 month treatment plan
[Phase 1]Botox Full upper face + mid-face Juvéderm® Voluma
[Week 4]2 Botox® follow-up + mid-face swelling reassessment after [ ] weeks
[Phase 2]Sofwave Full-face tightening
[Week 8]Volift / Volbella refining static lines
[Phase 3]PicoSure Pro × 3(every 4 weeks)
[Week 16]Skinvive Full face
[Week 24]Comprehensive outcome assessment + maintenance plan development
[Annual]Personalized maintenance (Botox® every 4 months / fillers every 12–18 months / Sofwave™ every 18 months)
Fine-tuning at every follow-up visit
- Static + dynamic photo comparison
- client subjective satisfaction score (0–10)
- Feedback from those around you (partner / colleagues)
- Micro-adjustment or dissolution as needed
- Adjust SPF + skincare routine
Long-term annual maintenance
- Botox Every 3.5–4 months
- filler every 12–24 months (depending on the formulation)
- Sofwave every 18–24 months
- PicoSure Maintenance every 6 months
- Skinvive Every 6 months
- Annual full-face harmony reassessment
How soon will we see results from a comprehensive wrinkle plan, and how long does each treatment last?
The three tables below answer the three most frequently asked questions.
Timeline for each treatment’s results
| Treatment | First visit | Optimal |
|---|---|---|
| Botox(dynamic lines) | 3–7 day | 2 week |
| Voluma(mid-face) | Immediate | 2 Weeks for swelling to resolve |
| Volift/Volbella | Immediate | 2 Weeks for swelling to resolve |
| Sofwave | 3 months | 6 months |
| PicoSure Pro | 4 weeks (after each session) | 3–4 cumulative sessions |
| Skinvive | 2 week | 4 weeks (after 2–3 sessions) |
Duration of results per treatment
| Treatment | Maintenance cycle |
|---|---|
| Botox | 3.5–4 months |
| Voluma XC | 18–24 months |
| Volift | 12–15 months |
| Volbella | 9–12 months |
| Sofwave | 18–24 months |
| PicoSure Skin rejuvenation | 6 months (followed by maintenance) |
| Skinvive | 6 months |
Time required to complete the combination plan
| Plan scope | Completion timeline | Description |
|---|---|---|
| Baby Botox Single treatment | 1 sessions + 2 weeks | Simple |
| Botox + Filler | 2–4 week | 2 visit |
| Comprehensive moderate | 3–4 months | Delivered in 3–4 phases |
| Comprehensive depth | 6–9 months | Delivered in 5–6 phases |
Am I a candidate for a comprehensive wrinkle treatment plan?
the following questions most answers “yes”, You may benefit significantly more from a combination approach.
6 Quick self-assessment
- Presence of facial Multiple types wrinkles (dynamic + static + volume + surface)?
- Feel that Botox® alone or fillers alone limited efficacy?
- yes 3–6 months time to commit to a phased treatment plan?
- Willing to commit to“less is more” principle (micro-dosing, multiple sessions)?
- yes Special occasion (Looking to achieve a noticeably younger appearance before a special occasion (wedding, reunion, etc.)?
- yes“Natural + harmonious” have realistic expectations for the outcomes?
You are a good candidate for a comprehensive plan if you:
- 25 years of age or older, in overall good health
- Multiple types of wrinkles present
- willing to commit to a phased treatment plan
- yes “Natural + harmonious” Realistic expectations about outcomes
- Not pregnant or breastfeeding
- No neuromuscular disorders (contraindication to Botox®)
- no allergy to hyaluronic acid
- willing to commit to long-term maintenance
Treatment may not be suitable, or requires careful evaluation, if you:
- Pregnancy / breastfeeding
- Known allergy to Botox® or hyaluronic acid
- Myasthenia gravis / Lambert-Eaton syndrome
- Recent major facial surgery or procedure
- Keloid-prone skin (exercise caution with fillers)
- Severe deep-tissue ptosis (may require surgical intervention)
- Expectations “completed in one session + immediate results”
- unwilling to commit to a phased approach or ongoing maintenance
- budget does not allow for a comprehensive plan
Why do MedSpa “Wrinkle treatment package” often fall short of expectations?
Client G — 45-year-old Asian female · multi-layered aging concerns · previously treated at a medspa “Full-Face Botox® Package” 6 Dissatisfied after [ ] sessions
Going to a medspa Single-treatment package · standardized
- Without a layered diagnostic approach
- “Full-face Botox® 50 units” standard package
- Volume loss not assessed
- does not assess retaining ligament laxity
- epidermal texture is not assessed
- None “Phased” concept
- Outcome: dynamic lines resolved, but static lines remain and sagging persists
- How clients feel “Still looks aged — just without wrinkles”
At Luowei Medical Aesthetics Clinic layered, comprehensive · systematic approach
- Comprehensive 4-layer stratified diagnosis
- Dynamic lines: full upper-face Botox® 40 units
- Volume: Voluma mid-face 1.5 ml
- Retaining ligaments: Sofwave™ full-face, 1 session
- Static: Juvéderm® Volift for nasolabial folds 0.6 ml
- Epidermis: PicoSure × 3 sessions
- Hydration: Skinvive full face
- Staged execution over 4 months
- Outcome: overall appearance 7–8 years younger · client highly satisfied
Why Trust Luowei Medical Aesthetics Clinic for Your Comprehensive Wrinkle Treatment Plan?
Google's E-E-A-T framework evaluates medical content across four dimensions. Below are the specific credentials supporting every claim on this page.
Real clinical experience
- 80,000 cumulative injectable and combination treatment procedures
- 15,000+ Case-based layered combination treatment design
- Many medspas “package-based” Revision of failed treatments
- three-angle photography + dynamic video records for every client
- 4-Layer Facial Wrinkle Stratified Diagnostic System
- Multimodal combination plan design (injectables + energy-based + surface treatments)
- dual training in Asian anatomy and cultural aesthetics
Industry-recognized accreditation
- Every medical claim on this page is anchored to a named, clickable source — see Evidence & references below
Transparent and verifiable
- Written informed consent form signed before each treatment
- All Before & After photos are unretouched
Comprehensive wrinkle treatment is not “using more products”, yes “Layered diagnosis + harmonized treatment design”
This is why Luowei’s comprehensive treatment program is led by our physician as holding dual trainer status for both Botox and Juvéderm® physician-led treatment design — a comprehensive perspective that is extremely rare among Asian physicians in North America.
About the cost of comprehensive wrinkle treatment
Comprehensive wrinkle treatment and “A single Botox® treatment” The most significant difference is that it is essentially a multimodal plan spanning 3–6 months, An integrated combination of injectable, energy-based, and surface-level skin treatments working together. Ask “How much does the full plan cost?” has limited meaning here — because two individuals who appear “Same age” clients, treatment plans can vary enormously: one person may need only Botox + Voluma + Skinvive, while another may require a full protocol of Botox + Voluma + Volift + Sofwave + PicoSure × 3 + Skinvive. Think of it as “6 month medical rejuvenation program + long-term maintenance” rather than “Single-session cost”, decisions become rational and returns are maximized.
At Luowei Medical Aesthetics Clinic, combination plans Physician-led treatment design. Injectable treatments (Botox® and the full Juvéderm® line) are typically performed by the physician directly — because facial vascular anatomy is complex, dosing precision is critical, and dynamic outcomes require real-time clinical judgment. These factors directly determine how natural and safe your results will be. For energy-based treatments (Sofwave™ and PicoSure Pro), protocols and parameters are designed by the physician and may be carried out by our trained medical team. Procedures performed under direct physician supervision carry a different cost structure. Treatments such as superficial resurfacing and annual maintenance can be arranged more efficiently, while complex revision cases, advanced aging concerns, or clients with specific medical backgrounds are best served with full physician involvement throughout.
We do not publish a standardized price list online, because the cost of a combination plan “Pricing” If treated in isolation from personalized diagnosis and goals discussing it in isolation is inherently misleading. Following your Free 30-Minute Consultation, our physician will present a clear, phased, personalized treatment plan based on your layered diagnostic findings — including a transparent cost structure and prioritization recommendations. We encourage you to approach comprehensive rejuvenation as“5–10 years of investment in your health and appearance” rather than “a one-time expenditure” Taking time to reflect leads to more informed decisions — and more consistent, lasting results.Treatment decisions should be driven by your needs, not by price..
- Payment is made at the clinic, after the consultation and before treatment begins
- Nothing is paid in advance, and no deposit is required to hold an appointment
- Cosmetic treatment is a self-pay item and is not covered by public medical insurance in China
- All new clients receive a complimentary 30-minute Free Consultation & assessment
Common Risks, Contraindications & Safety Protocols for Combination Plans
Combination treatment plans involve multiple procedures, each carrying its own risk profile. It is our responsibility to communicate all possible reactions clearly and transparently.
Common reactions (by treatment)
- Botox: Bruising at injection sites (3–7 days) · temporary headache · localized tenderness
- Dermal filler (full Juvéderm® range): Swelling 24–72 hours · Bruising 3–7 days
- Sofwave: Mild warmth for 2–4 hours post-treatment · mild swelling
- PicoSure Pro: Swelling for 24 hours post-treatment · fine crusting
- Skinvive: Minor localized blister-like sensation resolving within 48 hours
Serious risks (rare, but important to disclose)
- filler-related vascular occlusion— the most serious complication (risk significantly reduced when the physician has thorough anatomical knowledge and uses blunt cannulas)
- Botox Diffusion to adjacent muscles— ptosis (upper eyelid droop) / asymmetric expression (avoidable with precise dosing)
- Filler nodules / asymmetry— Reversible with hyaluronidase if needed
- Infection— Strictly aseptic technique to minimize risk
- allergic reaction— Rare
- Post-inflammatory hyperpigmentation (PIH)— Laser treatments carry specific risks for Asian skin types; with a physician-led protocol, these risks are manageable
Relative contraindications (require careful evaluation)
- Anticoagulant therapy (increased bruising risk)
- Recent major dental or facial surgery
- Vaccination within the past 2 weeks
- active autoimmune disease
- Recent intentional tanning (laser component)
- Photosensitizing medications (relevant to the laser component)
Absolute contraindications (treatment not performed)
- Pregnancy / breastfeeding
- Botox Protein or hyaluronic acid allergy
- Myasthenia gravis / Lambert-Eaton syndrome
- Active facial infection
- oral Accutane use within the past 6 months (for laser treatments)
- Keloid-prone skin (exercise caution with fillers)
- Unrealistic expectations (“turning back the clock all at once”)
Safety protocols strictly enforced by our physician
- all injections performed personally by our physician
- Blunt cannulas are prioritized for filler in high-risk zones
- Every patient signs a written informed consent form prior to treatment
- hyaluronidase and a vascular occlusion emergency protocol are always on hand at the clinic
- Imaging archived after every session with rigorous follow-up
- Phased execution, not “doing everything in one session”
Additional Comparison & Reference Data
| Typical areas | Forehead lines, glabellar 11 lines, crow’s feet |
|---|---|
| At rest | Invisible or extremely faint |
| During expression | Pronounced |
| Underlying mechanism | Repeated contraction of mimetic muscles |
| First-choice treatment | Botox / Dysport Micro-dose protocol |
| Typical areas | Nasolabial folds, marionette lines, neck lines, perioral lines |
|---|---|
| At rest | Clearly visible |
| During expression | Deeper |
| Underlying mechanism | Dermal fibre breakdown + volume loss |
| First-choice treatment | Juvéderm Hyaluronic acid + Sculptra / Radiesse |
Where the medical claims on this page come from
Everything above about Comprehensive Wrinkle Treatment rests on published evidence rather than on our own word. The sources below are the ones behind those statements: peer-reviewed papers indexed in PubMed, and guidance written for patients by dermatology academies and national health services. Read them before you decide — and bring any of them to your consultation.
- Peer-reviewedBotulinum toxin type A for facial wrinkles
- Peer-reviewedBotulinum Toxin Treatment for Mild to Moderate Platysma Bands: A Systematic Review of Efficacy, Safety, and Injection Technique
- Patient guidanceWrinkles
- Patient guidanceDermal fillers: Overview
- Patient guidanceBotulinum toxin: Overview
What these references can and cannot tell you. They describe what is known about the treatment itself — how well it tends to work, how long results last, and what can go wrong. They are not an assessment of this clinic, and no published study can tell you whether it suits your skin type, anatomy, or medical history. That judgement comes from the physician who examines you in person, and it may well be “not this one”.